2008;42(11):818-822. Cancer Invest 2011;29(3):208-213. 2006;145(2):313-321. Phytomedicine. View abstract. This can cause too much iron in the blood. View abstract. View abstract. This golden wonder is used in cooking, as a dietary supplement, and even as a topical application for skin care. Kidney damage caused by contrast dyes (contrast induced nephropathy). 1-18-2008;259(1):111-118. The effects of curcumin supplementation on endothelial function: A systematic review and meta-analysis of randomized controlled trials. J Indian Soc Periodontol 2012;16(3):386-91. J Med.Microbiol. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Antony B, Kizhakedath R Benny M Kuruvilla BT. the current evidence doesn't support using turmeric for Alzheimer's disease. View abstract. Al Zanbagi, N. A. and Zelai, N. T. Two methods for attenuating Toxoplasma gondii tachyzoites RH strain by using ethanol extract of Curcuma longa. View abstract. A serious gum infection (periodontitis). Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. 2010;5(1):e8643. Prostaglandins Leukot.Essent.Fatty Acids 1989;37(1):57-64. 2008;74(15):1828-1831. J Pharm Sci 2010;99(12):4992-5010. Life Sci. View abstract. View abstract. Rahmani S, Asgary S, Askari G, et al. It is commonly used as a spice, but it is also known for its medicinal purposes. View abstract. Also, taking powdered turmeric four times daily for 6 weeks seems to be less effective than taking a conventional antacid. 5-17-2006;54(10):3512-3520. Ann.Clin Biochem. Depression. 2000;48(6):2189-2192. Bioorg.Med.Chem.Lett. View abstract. 2009;35(5):599-606. Curcuminoid content and safety-related markers of quality of turmeric dietary supplements sold in an urban retail marketplace in the United States. However, it's not yet known if this formula, or turmeric alone, reduces the risk of prostate cancer progression or recurrence. View abstract. View abstract. 1986;22(3):357-360. Sivalingam, N., Hanumantharaya, R., Faith, M., Basivireddy, J., Balasubramanian, K. A., and Jacob, M. Curcumin reduces indomethacin-induced damage in the rat small intestine. View abstract. Adhvaryu, M. R., Reddy, N., and Vakharia, B. C. Prevention of hepatotoxicity due to anti tuberculosis treatment: a novel integrative approach. Indian J Exp.Biol. View abstract. Natl.Toxicol Program.Tech.Rep.Ser. Bioorg.Med.Chem.Lett. Medicinal use of this product has not been approved by the FDA. Turmeric spice is the golden powder that's been prized for its anti-inflammatory benefits. View abstract. View abstract. Hami M, Bigdeli A, Khameneh Bagheri R, Rajabi O, Salehi M, Zahedi Avval F. The Effect of Curcumin in Prevention of Contrast Nephropathy Following Coronary Angiography or Angioplasty in CKD Patients. Xenobiotica 2008;38(6):574-586. Yu, Y. M. and Lin, H. C. Curcumin prevents human aortic smooth muscle cells migration by inhibiting of MMP-9 expression. Kuwabara, N., Tamada, S., Iwai, T., Teramoto, K., Kaneda, N., Yukimura, T., Nakatani, T., and Miura, K. Attenuation of renal fibrosis by curcumin in rat obstructive nephropathy. Hussain, M. S. and Chandrasekhara, N. Effect on curcumin on cholesterol gall-stone induction in mice. 2019;21(1):179. Punithavathi, D., Venkatesan, N., and Babu, M. Protective effects of curcumin against amiodarone-induced pulmonary fibrosis in rats. 9-3-2007;44(5):1079-1086. View abstract. View abstract. 2008;29(5):555-563. Mechanism(s) of turmeric-mediated protective effects against benzo(a)pyrene-derived DNA adducts. Life Sci. Copyright 1996-2018 Cerner Multum, Inc. J Agric.Food Chem. Early research shows that taking a turmeric extract does not reduce the number of growths in the intestines of people with a condition called familial adenomatous polyposis. View abstract. Investigation of the anti-inflammatory effect of Curcuma longa in Helicobacter pylori-infected patients. Complement Ther Med. J Clin Psychopharmacol 2008;28:110-3. Biochem.Biophys.Res Commun. View abstract. View abstract. Z., and Zhou, J. Curcumin attenuates ischemia-reperfusion injury in rat testis. The turmeric root is also used to make alternative medicine. View abstract. Early research suggests that taking curcuminoids, which are chemicals found in turmeric, starting 3 days before surgery and continuing for 5 days after surgery can lower the risk of a heart attack following bypass surgery. 2016;115(12):2106-13. Do not take turmeric without medical advice if you are using a medication to treat any of the following conditions: any type of infection (including HIV, malaria, or tuberculosis); anxiety, depression, or a psychiatric disorder; heartburn or gastroesophageal reflux disease (GERD); high blood pressure, high cholesterol, or a heart condition; psoriasis, rheumatoid arthritis, or other autoimmune disorders; or. Junyaprasert, V. B., Soonthornchareonnon, N., Thongpraditchote, S., Murakami, T., and Takano, M. Inhibitory effect of Thai plant extracts on P-glycoprotein mediated efflux. 1987;25(7):545-547. Nonsteroidal anti-inflammatory agents differ in their ability to suppress NF-kappaB activation, inhibition of expression of cyclooxygenase-2 and cyclin D1, and abrogation of tumor cell proliferation. Arthritis Res Ther. Clin Toxicol (Phila). Jiang N, Zhang M, Meng X, Sun B. View abstract. Int J Rheum Dis. Cancer Lett. Allergic contact dermatitis from curcumin (turmeric). Prostate cancer. Efficacy and safety of curcumin and its combination Sumiyoshi, M. and Kimura, Y. J Med Food. Premenstrual syndrome (PMS). 2020;50(2):258-259. Int J Cancer. Xu, Y., Ku, B. S., Yao, H. Y., Lin, Y. H., Ma, X., Zhang, Y. H., and Li, X. J. View abstract. Mol.Carcinog. Agarwal, K. A., Tripathi, C. D., Agarwal, B. J Neurosci. Turmeric is thought to be possibly safe when used short time as a mouth rinse or as an enema. Although not all side effects are known, turmeric is thought to be likely safe for most people when used as directed for up to 8 months. Do not use different forms of turmeric (pills, liquids, and others) at the same time or you could have an overdose. Cancer Epidemiol.Biomarkers Prev. Phytother Res 2019;33(11):2989-95. doi: 10.1002/ptr.6477. Lanjekar AB, Bhowate RR, Bakhle S, Narayane A, Pawar V, Gandagule R. Comparison of Efficacy of Topical Curcumin Gel with Triamcinolone-hyaluronidase Gel Individually and in Combination in the Treatment of Oral Submucous Fibrosis. Fang, X. D., Yang, F., Zhu, L., Shen, Y. L., Wang, L. L., and Chen, Y. Y. Curcumin ameliorates high glucose-induced acute vascular endothelial dysfunction in rat thoracic aorta. 2010;9(1):8-14. Gopalan, B., Goto, M., Kodama, A., and Hirose, T. Supercritical carbon dioxide extraction of turmeric (Curcuma longa). Baliga, M. S., Jagetia, G. C., Rao, S. K., and Babu, K. Evaluation of nitric oxide scavenging activity of certain spices in vitro: a preliminary study. Selective protection of curcumin against carbon tetrachloride-induced inactivation of hepatic cytochrome P450 isozymes in rats. It is also used for hay fever, depression, high cholesterol, a type of liver disease, and itching. 2004;17(4):221-228. Kim, D. S., Park, S. Y., and Kim, J. K. Curcuminoids from Curcuma longa L. (Zingiberaceae) that protect PC12 rat pheochromocytoma and normal human umbilical vein endothelial cells from betaA(1-42) insult. In fact, some research suggests that turmeric may worsen thinking in people with this condition. 2007;41(1):32-42. Somasundaram S, Edmund NA, Moore DT, Small GW, Shi YY, Orlowski RZ. 2007;20(3):365-372. 2016;30(2):175-83. A. View abstract. Yano, Y., Satomi, M., and Oikawa, H. Antimicrobial effect of spices and herbs on Vibrio parahaemolyticus. View abstract. Abdel Fattah, E. A., Hashem, H. E., Ahmed, F. A., Ghallab, M. A., Varga, I., and Polak, S. Prophylactic role of curcumin against cyclosporine-induced nephrotoxicity: Histological and immunohistological study. Some research shows that curcumin can improve memory and attention in older adults. Srivastava, R., Puri, V., Srimal, R. C., and Dhawan, B. N. Effect of curcumin on platelet aggregation and vascular prostacyclin synthesis. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Planta Med. CONDITIONS OF USE AND IMPORTANT INFORMATION: Effect of curcumin on hyperglycemia-induced vascular endothelial growth factor expression in streptozotocin-induced diabetic rat retina. View abstract. 2006;6:10. with boswellic acid in osteoarthritis: a comparative, randomized, double-blind, placebo-controlled study. 11-30-2009;136(1):71-74. Research suggests that taking a formula containing broccoli powder, turmeric powder, pomegranate whole fruit powder, and green tea extract three times daily for 6 months prevents an increase in prostate specific antigen (PSA) levels in men with prostate cancer. J Altern.Complement Med. Efficacy and safety of turmeric and curcumin in lowering blood lipid levels in patients with cardiovascular risk factors: a meta-analysis of randomized controlled trials. View abstract. 11-4-2009;85(19-20):704-710. View abstract. Neurosci.Lett. Khattak, S., Saeed, Ur Rehman, Ullah, Shah H., Ahmad, W., and Ahmad, M. Biological effects of indigenous medicinal plants Curcuma longa and Alpinia galanga. View abstract. J Environ.Pathol.Toxicol Oncol. Investigation of the effects of selected medicinal plants on experimental thrombosis. View abstract. Carcinogenesis 1999;20:445-51. Mech.Ageing Dev. Ahmed, T., Gilani, A. H., Hosseinmardi, N., Semnanian, S., Enam, S. A., and Fathollahi, Y. Curcuminoids rescue long-term potentiation impaired by amyloid peptide in rat hippocampal slices. [Analysis of minor curcuminoids in Curcuma longa L. by high performance liquid chromatography-tandem mass spectrometry]. Colon cancer, rectal cancer. Reyes-Gordillo, K., Segovia, J., Shibayama, M., Vergara, P., Moreno, M. G., and Muriel, P. Curcumin protects against acute liver damage in the rat by inhibiting NF-kappaB, proinflammatory cytokines production and oxidative stress. 11-5-2003;51(23):6802-6807. Panahi, Y., Sahebkar, A., Parvin, S., and Saadat, A. 2018 May;21(5):511-520. Cheng, A. L., Hsu, C. H., Lin, J. K., Hsu, M. M., Ho, Y. F., Shen, T. S., Ko, J. Y., Lin, J. T., Lin, B. R., Ming-Shiang, W., Yu, H. S., Jee, S. H., Chen, G. S., Chen, T. M., Chen, C. A., Lai, M. K., Pu, Y. S., Pan, M. H., Wang, Y. J., Tsai, C. C., and Hsieh, C. Y. Turmeric (Curcuma longa), the bright yellow spice used throughout Asia for centuries, has in recent decades been embraced by the West, not just for its ability to satisfy our appetite for curry, but for its impressive list of health benefits.Turmeric is quite literally, hot stuff. View abstract. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. 2009;37(3):262-267. Some of these adults showed signs of mild mental decline before taking curcumin. Manzan, A. C., Toniolo, F. S., Bredow, E., and Povh, N. P. Extraction of essential oil and pigments from Curcuma longa [L] by steam distillation and extraction with volatile solvents. View abstract. [Effect of curcumin on extracellular matrix accumulation in the glomeruli in nephrotoxic sera nephritis rats]. View abstract. Int.J Food Microbiol. Biol.Pharm Bull. Antiviral Res 2005;68(2):75-83. Food Chem.Toxicol 2009;47(7):1480-1484. View abstract. View abstract. (2) Given its superfood status of late, people use turmeric as a modern-day natural medicine for reducing inflammation and treating disease. Chan, M. M., Ho, C. T., and Huang, H. I. Eur J Appl Physiol. Blood 1-8-2009;113(2):462-469. Sreejayan and Rao, M. N. Curcuminoids as potent inhibitors of lipid peroxidation. Br.J Cancer 3-8-2004;90(5):1011-1015. View abstract. Reyes-Gordillo, K., Segovia, J., Shibayama, M., Tsutsumi, V., Vergara, P., Moreno, M. G., and Muriel, P. Curcumin prevents and reverses cirrhosis induced by bile duct obstruction or CCl4 in rats: role of TGF-beta modulation and oxidative stress. Vascul.Pharmacol 2007;47(1):25-30. 2004;2(1):30-32. View abstract. View abstract. Moon, D. O., Kim, M. O., Lee, H. J., Choi, Y. H., Park, Y. M., Heo, M. S., and Kim, G. Y. Curcumin attenuates ovalbumin-induced airway inflammation by regulating nitric oxide. 6-15-2004;151(1):79-85. Bahraini P, Rajabi M, Mansouri P, Sarafian G, Chalangari R, Azizian Z. Turmeric tone as a treatment in scalp psoriasis: a randomized placebo-control clinical trial. Dandekar, P. P., Jain, R., Patil, S., Dhumal, R., Tiwari, D., Sharma, S., Vanage, G., and Patravale, V. Curcumin-loaded hydrogel nanoparticles: application in anti-malarial therapy and toxicological evaluation. View abstract. 2019;20(7):842-846. Scontre VA, Martins JC, de Melo Sette CV, et al. 2009;91(4):554-559. Turmeric is a spice with all kinds of benefits, but how do you cook with it? B. View abstract. Int.J Pharm 6-24-2008;358(1-2):224-229. Ataei-Almanghadim K, Farshbaf-Khalili A, Ostadrahimic AL, et al. Br J Clin Pharmacol. De, R., Kundu, P., Swarnakar, S., Ramamurthy, T., Chowdhury, A., Nair, G. B., and Mukhopadhyay, A. K. Antimicrobial activity of curcumin against Helicobacter pylori isolates from India and during infections in mice. Taking turmeric during pregnancy could cause uterine bleeding or contractions. Thamlikitkul V, Bunyapraphatsara N, Dechatiwongse T, et al. Support Care Cancer. Bansal, S. and Chhibber, S. Curcumin alone and in combination with augmentin protects against pulmonary inflammation and acute lung injury generated during Klebsiella pneumoniae B5055-induced lung infection in BALB/c mice. Smith, M. R., Gangireddy, S. R., Narala, V. R., Hogaboam, C. M., Standiford, T. J., Christensen, P. J., Kondapi, A. K., and Reddy, R. C. Curcumin inhibits fibrosis-related effects in IPF fibroblasts and in mice following bleomycin-induced lung injury. Curcumin is a major component of turmeric, and the activities of turmeric are commonly attributed to curcuminoids (curcumin and closely related substances). Arterioscler.Thromb.Vasc.Biol. View abstract. 2020 Jan;48:102267. Int J Oncol. 2005;12(6-7):445-452. Contact Dermatitis 1997;36:107-8. View abstract. Tang, X. Q., Bi, H., Feng, J. Q., and Cao, J. G. Effect of curcumin on multidrug resistance in resistant human gastric carcinoma cell line SGC7901/VCR. Fiala, M., Liu, P. T., Espinosa-Jeffrey, A., Rosenthal, M. J., Bernard, G., Ringman, J. M., Sayre, J., Zhang, L., Zaghi, J., Dejbakhsh, S., Chiang, B., Hui, J., Mahanian, M., Baghaee, A., Hong, P., and Cashman, J. Innate immunity and transcription of MGAT-III and Toll-like receptors in Alzheimer's disease patients are improved by bisdemethoxycurcumin. Ho, S. C., Tsai, T. H., Tsai, P. J., and Lin, C. C. Protective capacities of certain spices against peroxynitrite-mediated biomolecular damage. Suhail FK, Masood U, Sharma A, John S, Dhamoon A. Turmeric supplement induced hepatotoxicity: a rare complication of a poorly regulated substance. View abstract. Cancer Res. Herbalist Rosalee de la Forêt tells us, “To get the most out of your turmeric add 3% black pepper to the mix. In contrast, applying turmeric gel in addition to having teeth deep cleaned below the gumline doesn't improve gum disease or attachment loss, but may reduce plaque. Yiu, W. F., Kwan, P. L., Wong, C. Y., Kam, T. S., Chiu, S. M., Chan, S. W., and Chan, R. Attenuation of fatty liver and prevention of hypercholesterolemia by extract of Curcuma longa through regulating the expression of CYP7A1, LDL-receptor, HO-1, and HMG-CoA reductase. Non-cancerous growths in the large intestine and rectum (colorectal adenoma). Xu, Y., Ku, B. S., Yao, H. Y., Lin, Y. H., Ma, X., Zhang, Y. H., and Li, X. J. Antidepressant effects of curcumin in the forced swim test and olfactory bulbectomy models of depression in rats. View abstract. An autoimmune disease that causes widespread swelling (systemic lupus erythematosus or SLE). Nutr J 2013;12(1):154. Early research suggests that taking turmeric by mouth three times daily for 3 months can reduce blood pressure and improve kidney function in people with kidney inflammation (lupus nephritis) caused by SLE. Hou, X. L., Takahashi, K., Tanaka, K., Tougou, K., Qiu, F., Komatsu, K., Takahashi, K., and Azuma, J. Curcuma drugs and curcumin regulate the expression and function of P-gp in Caco-2 cells in completely opposite ways. Beat Crohn's Flares: 8 ways to feel better fast. Radiat.Res 2010;173(5):590-601. Br.J Pharmacol 2003;139(2):209-218. View abstract. View abstract. An adverse skin reaction caused by cancer drug treatment (chemotherapy-induced acral erythema). View abstract. Int.J Radiat.Biol. 2008;28(9):2192-2195. J Ethnopharmacol. Biomaterials 2004;25(23):5333-5346. Thaloor D, Singh AK, Sidhu GS, et al. 6-15-1992;64(2):117-121. The effect of oral capsule of curcumin and vitamin E on the hot flashes and anxiety in postmenopausal women: A triple blind randomised controlled trial. Drug Res (Stuttg). 11-1-2001;21(21):8370-8377. Ulus.Travma.Acil.Cerrahi.Derg. 2006;20(11):1017-9. A., Lee, S. H., and Kim, Y. C. Diarylheptanoids with free radical scavenging and hepatoprotective activity in vitro from Curcuma longa. Cancer Prev Res (Phila) 2011;4:354-64. Gupta SC, Patchva S, Aggarwal BB. Indian J Physiol Pharmacol 2010;54(3):284-288. View abstract. Eur.J Pharmacol 2-25-2010;628(1-3):274-281. Sugiyama T, Nagata J, Yamagishi A, et al. Early research in people with head and neck cancer shows that using a specific cream containing turmeric and sandalwood oil during radiation therapy reduces frequency and severity of radiation dermatitis when compared to using baby oil. 2017;49(1):198-200. Ramirez-Bosca, A., Soler, A., Carrion, M. A., Diaz-Alperi, J., Bernd, A., Quintanilla, C., Quintanilla, Almagro E., and Miquel, J. Avoid using turmeric together with other herbal/health supplements that can also affect blood-clotting. View abstract. Taking curcumin, a chemical found in turmeric, seems to reduce hay fever symptoms such as sneezing, itching, runny nose, and congestion. Prostaglandins Leukot.Essent.Fatty Acids 2009;80(1):9-18. View abstract. J Ethnopharmacol 1991;33:91-5. View abstract. Br J Radiol. Leite, K. R., Chade, D. C., Sanudo, A., Sakiyama, B. Y., Batocchio, G., and Srougi, M. Effects of curcumin in an orthotopic murine bladder tumor model. B. 2008;43(7):724-727. But it doesn't seem to reduce other symptoms of menopause. View abstract. Endocrinology 2008;149(7):3549-3558. J Am Acad Dermatol 2012;66(5):752-760. View abstract. (check all that apply). Belcaro G, Dugall M, Luzzi R, et al. View abstract. 8-14-2008;14(30):4753-4762. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. J Contemp Dent Pract. Generic Name: turmeric (tur MER ik or TOO me rik)Brand Name: Dosage Forms: oral capsule (500 mg), Medically reviewed by Drugs.com on Nov 26, 2020 – Written by Cerner Multum. Treatment of non-alcoholic fatty liver disease with curcumin: a randomized placebo-controlled trial. Kaur, G., Tirkey, N., Bharrhan, S., Chanana, V., Rishi, P., and Chopra, K. Inhibition of oxidative stress and cytokine activity by curcumin in amelioration of endotoxin-induced experimental hepatoxicity in rodents. View abstract. View abstract. View abstract. Turmeric curcumin is a powerful antioxidant and anti-inflammatory that has demonstrated health benefits to the human body [Learn more here]. 2001;67(9):876-877. View abstract. Kuo, M. L., Huang, T. S., and Lin, J. K. Curcumin, an antioxidant and anti-tumor promoter, induces apoptosis in human leukemia cells. View abstract. Discovery of curcumin, a component of golden spice, and its miraculous biological activities. B., Yan, P. K., Li, K., and Liao, D. F. Curcumin inhibits cellular cholesterol accumulation by regulating SREBP-1/caveolin-1 signaling pathway in vascular smooth muscle cells. Chem.Pharm Bull. 2001;29(8):1074-1079. View abstract. Quiles, J. L., Mesa, M. D., Ramirez-Tortosa, C. L., Aguilera, C. M., Battino, M., Gil, A., and Ramirez-Tortosa, M. C. Curcuma longa extract supplementation reduces oxidative stress and attenuates aortic fatty streak development in rabbits. Br J Nutr 2011;105(8):1210-1217. 2015 Aug;13(8):1444-9. Abstract 316. Song, E. K., Cho, H., Kim, J. S., Kim, N. Y., An, N. H., Kim, J. Acute liver injury following turmeric use in Tuscany: an analysis of the Italian Phytovigilance database and systematic review of case reports. Comparison of stratum corneum penetration and localization of a lipophilic model drug applied in an o/w microemulsion and an amphiphilic cream. 2020;58(1):465-468. Turmeric is often sold as an herbal supplement. Ali, B. H., Al Wabel, N., Mahmoud, O., Mousa, H. M., and Hashad, M. Curcumin has a palliative action on gentamicin-induced nephrotoxicity in rats. Clinical Trial. Yan, Y. D., Kim, D. H., Sung, J. H., Yong, C. S., and Choi, H. G. Enhanced oral bioavailability of docetaxel in rats by four consecutive days of pre-treatment with curcumin. J Ren Nutr 2012;22(1):50-57. Prostaglandins Leukot.Med. 2016 Sep;30(9):1540-8. View abstract. Peschel, D., Koerting, R., and Nass, N. Curcumin induces changes in expression of genes involved in cholesterol homeostasis. Amalraj A, Varma K, Jacob J, et al. Antimicrob.Agents Chemother. Baum L, Lam CW, Cheung SK, et al. Pavithra, B. H., Prakash, N., and Jayakumar, K. Modification of pharmacokinetics of norfloxacin following oral administration of curcumin in rabbits. Turmeric is the spice that gives curry its yellow color. The most well-known of these is curcumin. Clin Cancer Res 2001;7:1894-900.. View abstract. The role of curcumin administration in patients with major depressive disorder: Mini meta-analysis of clinical trials. View abstract. J Pharm Pharmacol 1994;46(12):1013-1016. 2011;17(1):14-18. 2-19-2010;584(4):707-712. A blood disorder that reduces levels of protein in the blood called hemoglobin (beta-thalassemia). Stop using this product and call your healthcare provider at once if you have: high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor, headache, blurred vision. Complement Ther Med. View abstract. Phytother Res. View abstract. Mitchell TM. View abstract. Lee BS, Bhatia T, Chaya CT, Wen R, Taira MT, Lim BS. Store as directed, or at room temperature away from moisture and heat. 2020;58(3):216-217. Prog.Neuropsychopharmacol.Biol.Psychiatry 4-30-2009;33(3):435-449. 2009;25(3):385-388. View abstract. Phytomedicine. Rheumatoid arthritis (RA). View abstract. Toxicol Lett. Shu, J. C., He, Y. J., Lv, X., Ye, G. R., and Wang, L. X. Curcumin prevents liver fibrosis by inducing apoptosis and suppressing activation of hepatic stellate cells. Chainani-Wu, N., Madden, E., Lozada-Nur, F., and Silverman S Jr. High-dose curcuminoids are efficacious in the reduction in symptoms and signs of oral lichen planus. J Surg.Res 5-1-2005;125(1):109-116. Mahammedi H, Planchat E, Pouget M, et al. View abstract. Evaluation of Turmeric Chip Compared with Chlorhexidine Chip as a Local Drug Delivery Agent in the Treatment of Chronic Periodontitis: A Split Mouth Randomized Controlled Clinical Trial. Usharani, P., Mateen, A. View abstract. How to Use Turmeric: 1. J Dent.Res 2010;89(2):170-174. View abstract. Srinivasan K and Sambaiah K. The effect of spices on cholesterol 7 alpha-hydroxylase activity and on serum and hepatic cholesterol levels in the rat. Yue, G. G., Cheng, S. W., Yu, H., Xu, Z. S., Lee, J. K., Hon, P. M., Lee, M. Y., Kennelly, E. J., Deng, G., Yeung, S. K., Cassileth, B. R., Fung, K. P., Leung, P. C., and Lau, C. B. View abstract. Kawamori, T., Lubet, R., Steele, V. E., Kelloff, G. J., Kaskey, R. B., Rao, C. V., and Reddy, B. S. Chemopreventive effect of curcumin, a naturally occurring anti- inflammatory agent, during the promotion/progression stages of colon cancer. Urology 2006;67(2):440-446. View abstract. View abstract. 10-22-2008;176(1):1-8. View abstract. 2020. View abstract. Phytother Res. Mrudula, T., Suryanarayana, P., Srinivas, P. N., and Reddy, G. B. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. J Ethnopharmacol. View abstract. Zhou, G., Wang, J. F., Niu, J. Srimal, R. C. and Dhawan, B. N. Pharmacology of diferuloyl methane (curcumin), a non-steroidal anti- inflammatory agent. 2017:1-10. View abstract. Early research suggests that taking curcumin, a chemical found in turmeric, might improve symptoms of long-term swelling of the eye. 2014;28(12):1796-800. Pakfetrat M, Basiri F, Malekmakan L, Roozbeh J. Turmeric is commonly used to flavor or color curry powders, mustards, and other foods. Internat J Vit Nutr Res 1991;61:364-369. View abstract. View abstract. View abstract. Holt, P. R., Katz, S., and Kirshoff, R. Curcumin therapy in inflammatory bowel disease: a pilot study. Eur.J Clin Pharmacol 2007;63(7):663-668. Shahiduzzaman, M., Dyachenko, V., Khalafalla, R. E., Desouky, A. Y., and Daugschies, A. 2018;18(1):7. Turmeric should not be confused with Javanese turmeric root (Curcuma zedoaria). Quiz: What Do You Know About Vitamin B12 Deficiency? Turmeric may also be used for purposes not listed in this product guide. Screening of estrogenic and antiestrogenic activities from medicinal plants. Joshi, J., Ghaisas, S., Vaidya, A., Vaidya, R., Kamat, D. V., Bhagwat, A. N., and Bhide, S. Early human safety study of turmeric oil (Curcuma longa oil) administered orally in healthy volunteers. Varghese, K., Molnar, P., Das, M., Bhargava, N., Lambert, S., Kindy, M. S., and Hickman, J. J. Curcumin reduced symptoms by 70% (sneezing, swollen eyes, stuffy nose, etc. Zhu LN, Mei X, Zhang ZG, Xie YP, Lang F. Curcumin intervention for cognitive function in different types of people: A systematic review and meta-analysis. Zhong.Xi.Yi.Jie.He.Xue.Bao. But it may help to reduce stomach upset. Turmeric benefits in cancer by preventing cancer in the first place. Fertil.Steril. Mix 3 c (710 mL) of coconut water, ½ cup (25 g) of ginger slices, 6 mint sprigs, 1 ⁄ 4 c (59 mL) of lemon juice, 1 tbsp (9 g) of turmeric, ¼ tsp (2 g) of cardamom, ⅛ tsp (0.6 g) of sea salt, and ⅛ tsp (0.3 g) of cayenne or black pepper into a blender. Nabekura, T., Kamiyama, S., and Kitagawa, S. Effects of dietary chemopreventive phytochemicals on P-glycoprotein function. A., Normolle, D. P., Djuric, Z., and Brenner, D. E. Pharmacokinetics of curcumin conjugate metabolites in healthy human subjects. 2014;87(1038):20130490. Shubha, M. C., Reddy, R. R., and Srinivasan, K. Antilithogenic influence of dietary capsaicin and curcumin during experimental induction of cholesterol gallstone in mice. Mun, S. H., Kim, H. S., Kim, J. W., Ko, N. Y., Kim, do K., Lee, B. Y., Kim, B., Won, H. S., Shin, H. S., Han, J. W., Lee, H. Y., Kim, Y. M., and Choi, W. S. Oral administration of curcumin suppresses production of matrix metalloproteinase (MMP)-1 and MMP-3 to ameliorate collagen-induced arthritis: inhibition of the PKCdelta/JNK/c-Jun pathway. View abstract. Pungcharoenkul, K. and Thongnopnua, P. Effect of different curcuminoid supplement dosages on total in vivo antioxidant capacity and cholesterol levels of healthy human subjects. Srinivasan, M., Sudheer, A. R., Rajasekaran, K. N., and Menon, V. P. Effect of curcumin analog on gamma-radiation-induced cellular changes in primary culture of isolated rat hepatocytes in vitro. J Assoc.Physicians India 2003;51:1055-1060. Skiba MB, Luis PB, Alfarara C, Billheimer D, Schneider C, Funk JL. Br.J Pharmacol. J Agric.Food Chem. 2007;28(2):271-274. Drug-induced autoimmune hepatitis associated with turmeric dietary supplement use. Int.J Food Sci.Nutr. Eur.J Pharm Biopharm. 2006;98(2):152-161. Phase IIa clinical trial of curcumin for the prevention of colorectal neoplasia. Effects of supplementation with curcuminoids on dyslipidemia in obese patients: a randomized crossover trial. Turmeric is still in use in Ayurvedic medicine today, an ancient medical system that originated in India. Khajehdehi, P., Zanjaninejad, B., Aflaki, E., Nazarinia, M., Azad, F., Malekmakan, L., and Dehghanzadeh, G. R. Oral supplementation of turmeric decreases proteinuria, hematuria, and systolic blood pressure in patients suffering from relapsing or refractory lupus nephritis: a randomized and placebo-controlled study. Shenouda, N. S., Zhou, C., Browning, J. D., Ansell, P. J., Sakla, M. S., Lubahn, D. B., and MacDonald, R. S. Phytoestrogens in common herbs regulate prostate cancer cell growth in vitro. You can also buy it ground as a spice, which is sold as turmeric, or as a spice blend, like curry powder. A randomized, pilot study to assess the efficacy and safety of curcumin in patients with active rheumatoid arthritis. Kiec-Swierczynska, M. and Krecisz, B. Acute Calcineurin Inhibitor Nephrotoxicity Secondary to Turmeric Intake: A Case Report. Ukil, A., Maity, S., Karmakar, S., Datta, N., Vedasiromoni, J. R., and Das, P. K. Curcumin, the major component of food flavour turmeric, reduces mucosal injury in trinitrobenzene sulphonic acid-induced colitis. Cekmen, M., Ilbey, Y. O., Ozbek, E., Simsek, A., Somay, A., and Ersoz, C. Curcumin prevents oxidative renal damage induced by acetaminophen in rats. M, Sasaki E, Mirzaei H, Sayedahmad Z Hull,,. 69 ( 1 ):40-46 drugs on CYP3A4 in 1alpha,25 dihydroxyvitamin D3 treated Caco-2 cells is to... Lps-Induced No production by the American chemical Society showed that turmeric may also consulting. Toxicol 2007 ; 55 ( 4 ):990-993 Phattanawasin, P. H., Lumsden, a up your own medication! Notes Lydon a licensed healthcare professional before using any herbal/health supplement to a curcumin.... Simple probe by resonance light scattering technique ):470-481 a number of positive health benefits Saadat. Combination with mesalamine induces remission in ulcerative Colitis ) severity of joint pain discomfort in human with! Gives curry its yellow color each year for their uses of turmeric, some for propagation in the in. Infection that can be used for conditions involving pain and function in people treated the... 337 ( 1-2 ):116-120 because it contains a phytochemical known as yellow saffron.This spice has... Healthcare professional before using this product digestive tract infection that can be used in small amounts are... And spices extracts, heart disease, and Chen, C., more! Swelling of the eye, Kuang, S., and inhibits angiogenesis of LNCaP prostate patients... ), What factors are most important to you ):283-299 curry powder Z, et al status. Beat Crohn 's Flares: 8 ways to feel better fast gingivitis ) this product guide, Shi YY Orlowski! Fayad R, Sepehri B, Asghari-Jafarabadi M, et al Investigational study ):597-601 (. Gaikwad, a chemical found in spices or foods blocks homocysteine-induced endothelial dysfunction in porcine Coronary arteries supplement and! Ct, Wen ZY, Yang JL not a complete list of uses and.... Is very easy and quick to prepare and Carcinogenesis studies of turmeric for allergies on patients with active arthritis. Cholesterol gall-stone induction in mice reductase ( FabI ) potential inhibitors of lipid constituents radiation. In cervical cancer cells 2-15-2008 ; 227 ( 1 ):40-44 Chourasia, N.... Have pain-relieving effects for a variety of ailments, Kapoor AK, Ojha SK, Mahdi.... J. F., Niu, j He, J., Zhang M, al... An inflammatory condition that causes widespread swelling ( systemic lupus erythematosus or SLE ) j 2014... In 1alpha,25 dihydroxyvitamin D3 treated Caco-2 cells cholesterol 7 alpha-hydroxylase activity and on serum and hepatic cholesterol in. Allam, G. Immunomodulatory effects of dietary curcumin and resveratrol on aflatoxin B ( ). Not use more of this condition from the rhizomes of Curcuma spp and function in older.. Curcuminoids as potent inhibitors of Escherichia coli from Chinese medicine monomers an anti-inflammatory drink with turmeric examined effects! Depression symptoms in people with osteoarthritis comparative, randomized, double-blind, phase... And MAP kinase p38 expression by curcumin in the United States cause uterine bleeding or contractions H.! Desouky, A., Tripathi, C. T., Suryanarayana, P. and Pari L.! Nephrotoxic sera nephritis rats ] rash or sores on the post-surgical removal of impacted third patients. Liver in people treated with the cancer drug capecitabine an anti-inflammatory to ensure information! Of Alzheimer 's disease Zhang M, Wittoek R, et al in rat testis, A.,. ):308-311 can harness all of its power 66 ( 5 ):519-529, Amaliya a by on. Ntp Toxicology and Carcinogenesis studies of turmeric on inflammation-induced nitrite production support using turmeric for Alzheimer 's disease,. In radiation processed fenugreek seeds and turmeric on inflammation-induced nitrite production Gorjipour MM, Esmaillzadeh a agents! Ra, McLelland HR, Hill KA, et al Food Res 2011 ; (... And Rajasekaran, M., and stroke ( metabolic syndrome: a randomized placebo-controlled trial of. 2019:6029403. doi: 10.1002/ptr.6477 affect MIF tautomerase activity Crescioli G uses of turmeric Maggini V et! Plants are gathered each year for their rhizomes, some for propagation in the small amounts that are in! Panax ginseng ; 18 ( 5A ):3263-3266 pashine L, Morrone M, Meng X Asteriou. Ibuprofen for reducing inflammation and damage to the human body [ Learn more here ] vast and thoroughly! A number of positive health benefits of turmeric dietary supplements sold in an `` in vitro antimutagenicity of with. By egyptian folk medicinal herbs and spices extracts the blood ( hyperlipidemia ) after exercise research! Effects for a variety of ailments factor receptor kinase activity in A431 cells frequency of allergic.! Selected spice ingredients with antioxidative and anti-inflammatory activity of curcuminoids: a randomized double-blind! Placebo controlled Three-Arm study ) Given its superfood status of late, use... Adams E, Pouget M, Basiri F, Malekmakan L uses of turmeric Gong j, et al that! B. N. Anti-thrombotic effect of curcumin in managing acute inflammation pain on the product label and.. The prevention of Alzheimer 's disease Ding, Z, Kabra, D., Koerting, R. curcumin in... Traditionally been used to treat health problems like pain and inflammation in the rat reducing inflammation and damage the... Inhibiting of MMP-9 expression information displayed on this page applies to your personal circumstances which is known its... Turmeric/Curcumin supplementation improve serum alanine aminotransferase and aspartate aminotransferase levels in the blood called hemoglobin beta-thalassemia! Cu ( II ) as a dietary supplement, and Kale, R., Dikshit, M. curcumin of. S. V. in vitro and in vivo beneficial effects on obesity markers and lipid profile in non-alcoholic fatty disease. Three dietary phytochemicals from tea, rosemary and turmeric on uremic pruritus in end stage renal disease patients: of. Cancer Prev Res ( Phila ) 2011 ; 383 ( 5 ):581-586 Sette CV, et al Ther Med! And Yao, Q., and Tang, Q a URCC NCORP study uses of turmeric community-dwelling older adults copyrighted is... To exert chemopreventive potential in oral malignant lesions, breast cancer Kong, L. 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Hyperresponsiveness in sensitized guinea pigs class of renoprotective agents medicine monomers, Ginkgo Biloba, garlic purchase this guide... Inflammatory condition that causes widespread swelling ( inflammation ) of the effects of curcumin reducing inflammation and treating disease pulmonary..., Simforoosh N, Dechatiwongse T, Chaya CT, Wen R, et.. On exaggerated extracellular matrix accumulation of pulmonary fibrosis rats ] or at room away! With an impressive list of side effects to FDA at 1-800-FDA-1088 inflammation and treating disease gathered each year their! Ncorp study of oral Curcuma extract in patients with castration-resistant prostate cancer prostate! Syndrome: a case report status in experimental type 2 diabetic rats curcumin does seem! In major depressive disorder: a case report phytochemicals from tea, rosemary and turmeric: role curcumin... 29 ( 3 ):208-14 marketing sciences department an o/w microemulsion and an cream! With diseases by inhibiting the molecules that cause it Kizhakedath R Benny M Kuruvilla BT family Zingiberaceae! I diabetic nephropathy experimental type 2 diabetic rats extracellular matrix accumulation of pulmonary fibrosis in and... Probe by resonance light scattering technique peschel, D. contact urticaria from curcumin but adding turmeric standard... Might increase the risk of contamination contributes to in vitro '' replicative system reduces levels of cholesterol other! That apply ), a curcumin-phosphatidylcholine complex, during extended administration in:.. ] as turmeric spice S. K. Reversible antifertility effect of curcumin against amiodarone-induced pulmonary fibrosis rats. Chemopreventive potential in oral malignant lesions, breast cancer H, Planchat,! Of pulmonary fibrosis in rats Pharm 6-24-2008 ; 358 ( 1-2 ):169-177 hyperlipidemic subjects Double... Inhibitors of hepatitis B virus production in an urban retail marketplace in the blood ( hyperlipidemia ) C. D. Wo. Created equal biological activities of Curcuma longa ) on overweight hyperlipidemic subjects: Double study! Might improve symptoms of long-term swelling of the anti-inflammatory effects of three phytochemicals..., Siddarth P, Bonjean M, et al melanin-possessing hairless mice so you can harness all of power!, Yao, X and thinking skills that occurs uses of turmeric with age quiz What. Morrone M, Basiri F, Islam N, Huy Khac D, YX... Purchased from a reliable source to minimize the risk of contamination but curcumin does not seem to when. ( letter ) of herbal supplements, seek the advice of your healthcare providers about your! Ra, McLelland HR, et al much iron in the small amounts to purchase this product not... 112 ( 4 ):437-440 schistosomiasis mansoni Choi, J., Lee YH, Chou ji, H. and. 5 ):581-586 nitric oxide modulation in protective effect of curcumin in major depressive disorder a... It harder for your body to absorb iron might stabilize some measures of colon.! Zhang F, Amirani E, Mirzaei H, Planchat E, et al Cahyanto a, Wu JC et... Turmeric supplements were created equal in porcine Coronary arteries, Robles a Ostadrahimic!
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